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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCRTR1
All Species:
30.91
Human Site:
Y45
Identified Species:
56.67
UniProt:
O43613
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43613
NP_001516.2
425
47536
Y45
D
Y
L
Y
P
K
Q
Y
E
W
V
L
I
A
A
Chimpanzee
Pan troglodytes
XP_524646
425
47381
Y45
D
Y
L
Y
P
K
Q
Y
E
W
V
L
I
A
A
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
N11
I
G
T
E
A
D
E
N
Q
T
V
E
E
M
K
Dog
Lupus familis
XP_544446
502
56267
Y122
D
Y
L
Y
P
K
Q
Y
E
W
V
L
I
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P58307
416
46748
Y45
D
Y
L
Y
P
K
Q
Y
E
W
V
L
I
A
A
Rat
Rattus norvegicus
P56718
416
46781
Y45
D
Y
L
Y
P
K
Q
Y
E
W
V
L
I
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507023
412
46359
Y42
D
Y
L
Y
P
K
Q
Y
E
W
A
L
I
V
A
Chicken
Gallus gallus
Q9DDN6
385
43491
E15
G
E
E
N
Q
T
D
E
M
K
M
E
L
F
T
Frog
Xenopus laevis
P70031
453
51139
N67
K
P
S
P
S
D
L
N
L
W
V
R
I
V
M
Zebra Danio
Brachydanio rerio
NP_001073337
424
48183
Y53
E
Y
L
H
P
K
Q
Y
E
W
V
L
I
A
G
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
I48
P
S
T
A
A
I
F
I
V
S
Y
L
L
I
F
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120335
399
45437
S29
S
L
D
Y
T
D
E
S
D
Y
N
A
T
N
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789606
462
52471
Y54
E
M
V
Y
P
Q
T
Y
E
W
V
I
L
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
25.8
78.8
N.A.
91.7
91.5
N.A.
81.8
26.5
24.5
61.1
26
N.A.
35.7
N.A.
32.9
Protein Similarity:
100
96.4
46.3
81
N.A.
93.8
93.6
N.A.
85.6
47.5
47.4
73.1
42.9
N.A.
51.7
N.A.
51.5
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
86.6
0
20
80
6.6
N.A.
6.6
N.A.
40
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
86.6
13.3
20
93.3
13.3
N.A.
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
0
0
0
0
0
8
8
0
47
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
47
0
8
0
0
24
8
0
8
0
0
0
0
0
0
% D
% Glu:
16
8
8
8
0
0
16
8
62
0
0
16
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
16
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
8
0
0
0
8
62
8
0
% I
% Lys:
8
0
0
0
0
54
0
0
0
8
0
0
0
0
8
% K
% Leu:
0
8
54
0
0
0
8
0
8
0
0
62
24
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
8
0
0
8
8
% M
% Asn:
0
0
0
8
0
0
0
16
0
0
8
0
0
8
0
% N
% Pro:
8
8
0
8
62
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
54
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
8
8
0
8
0
0
8
0
8
0
0
0
0
0
% S
% Thr:
0
0
16
0
8
8
8
0
0
8
0
0
8
0
8
% T
% Val:
0
0
8
0
0
0
0
0
8
0
70
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% W
% Tyr:
0
54
0
62
0
0
0
62
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _